Caveats: The Spotify interface works only if you have a premium account. I don't know if that's true for the others, but it does also support Sirius, Pandora, Last.fm, and a whole bunch of others.
My remote stopped working almost immediately. Fortunately there is an Onkyo remote app (v2, iPhone & Android) which serves quite well, and unlike with some electronics, you can still get to all the functions from the front panel.
Last, for setting up your speaker system, the "Setup" menu can be accessed repeatedly, so any time you add, remove or change speakers you just run the auto-configuration/equalization with the setup mic. You don't even have to tell it how many speakers you have.
The manual on the CD is kind of crappy but it pointed me in enough of the right directions that I was able to get things configured more or less the way I wanted them in one evening.